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He essentially committed suicide." [179] Biographer Walter Isaacson reported on Jobs's opposition to surgery, quoting Jobs as saying, "I didn't want my body to be opened, I didn't want to be violated in that way." [180] According to Isaacson, "for nine months he refused to undergo surgery for his pancreatic cancer a decision he later regretted as his health declined." [181] "Instead, he tried a vegan diet, acupuncture, herbal remedies, and other treatments he found online, and even consulted a psychic

When smokers inhale, nicotine reaches the brain within seconds, triggering the release of dopamine and other neurotransmitters that create feelings of pleasure and relaxation

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